The genus name Trillium comes from “tri” referring to the flower parts occurring in threes and llium from ‘liliaceous’, referring to the funnel-shaped flower.
The specific epithet grandiflorum comes from the Latin word ‘grandis’ meaning “grand and large”; ‘flora’ has the meaning of “goddess of flowers” referring to the large white flower.
Trilliums are generally divided into two major groups, pedicellate and sessile. In the pedicellate trilliums, the flower sits upon a pedicel that extends from the whorl of bracts, either “erect” above the bracts or “nodding” recurved under the bracts. In the sessile trilliums, there is no pedicel, and the flower appears to arise directly from the bracts. Large White Trillium falls within the pedicellate group.
Joseph E. Meyer claimed in a 1918 publication that an astringent tonic could be derived from the roots of Trillium in controlling bleeding and diarrhea.
The foliage of Trillium may be cleaned, cooked, and served like greens, but it would be a shame to kill such a beautiful plant. Berries and roots are poisonous, although they have low toxicity if eaten.